Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 5/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12133581 | 1.00 | POLB (0.54) | POLBLTA4HHTR2AHRH1SIGMAR1 | |
| SCHEMBL13278472 | 0.95 | POLB (0.61) | POLBLTA4HHTR2AHRH1SIGMAR1 | |
| SCHEMBL1162536 | 0.85 | POLB (0.56) | POLBLTA4HHTR2A | |
| SCHEMBL8854588 | 0.85 | POLB (0.56) | POLBLTA4HHTR2A | |
| SCHEMBL1162602 | 0.85 | POLB (0.56) | POLBLTA4HHTR2A | |
| SCHEMBL3646814 | 0.84 | LTA4H (0.47) | LTA4H | |
| SCHEMBL3643848 | 0.84 | LTA4H (0.47) | LTA4H | |
| SCHEMBL3642599 | 0.83 | TAAR1 (0.48) | POLB | |
| SCHEMBL2937792 | 0.81 | POLB (0.63) | POLBLTA4HSIGMAR1 | |
| SCHEMBL9469575 | 0.81 | POLB (0.63) | POLBLTA4HSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883627-B1 | BIR DOMAIN BINDING COMPOUNDS | PHARMASCIENCE INC (CA) | 2018-04-18 | — | — | EP | disclosed |