Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 10/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 5/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9469837 | 1.00 | MME (0.59) | MMEALDH1A1GAATSHRCAPN1 | |
| SCHEMBL5924918 | 0.94 | MME (0.59) | MMEALDH1A1GAATSHRCAPN1 | |
| SCHEMBL9470220 | 0.91 | MME (0.60) | MMEALDH1A1GAATSHRCAPN1 | |
| SCHEMBL9470216 | 0.91 | MME (0.60) | MMEALDH1A1GAATSHRCAPN1 | |
| SCHEMBL9469848 | 0.90 | MME (0.72) | MMEALDH1A1GAATSHRCAPN1 | |
| SCHEMBL9469850 | 0.90 | MME (0.72) | MMEALDH1A1GAATSHRCAPN1 | |
| SCHEMBL9469802 | 0.88 | MME (0.50) | MMEALDH1A1GAATSHRCTSL | |
| SCHEMBL9469805 | 0.88 | MME (0.50) | MMEALDH1A1GAATSHRCTSL | |
| SCHEMBL9469547 | 0.84 | MME (0.77) | MMEALDH1A1GAATSHRCAPN1 | |
| SCHEMBL9469545 | 0.84 | MME (0.77) | MMEALDH1A1GAATSHRCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192800-A | Hypotensive agents | PFIZER INC. (US) | 1993-03-09 | — | — | US | disclosed |
| US-5030654-A | Glutaramide diuretic agents | PFIZER INC. (US) | 1991-07-09 | — | — | US | disclosed |