Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 4/20 | 1.00 |
| ▸ | BRD4 | O60885 | 14/20 | 0.69 |
| ▸ | BRD2 | P25440 | 14/20 | 0.69 |
| ▸ | BRD3 | Q15059 | 14/20 | 0.69 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.61 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9469193 | 0.90 | CCKBR (1.00) | CCKBRBRD4BRD2BRD3SENP1 | |
| SCHEMBL11981915 | 0.82 | BRD4 (0.84) | CCKBRBRD4BRD2BRD3SENP1 | |
| SCHEMBL14756006 | 0.82 | BRD4 (1.00) | CCKBRBRD4BRD2BRD3 | |
| SCHEMBL9470080 | 0.82 | BRD4 (1.00) | CCKBRBRD4BRD2BRD3 | |
| SCHEMBL29823659 | 0.82 | BRD4 (1.00) | CCKBRBRD4BRD2BRD3 | |
| SCHEMBL11981911 | 0.79 | BRD4 (0.78) | CCKBRBRD4BRD2BRD3SENP1 | |
| SCHEMBL11961492 | 0.79 | BRD4 (0.78) | CCKBRBRD4BRD2BRD3SENP1 | |
| SCHEMBL11961489 | 0.79 | BRD4 (0.75) | CCKBRBRD4BRD2BRD3SENP1 | |
| SCHEMBL3788080 | 0.79 | SCN9A (0.78) | CCKBRBRD4BRD2BRD3SENP1 | |
| SCHEMBL6993452 | 0.79 | SCN9A (0.78) | CCKBRBRD4BRD2BRD3SENP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185331-A | Administering to treat panic and anxiety disorders | MERCK & CO., INC. (US) | 1993-02-09 | — | — | US | disclosed |
| EP-0514125-A1 | Triazolobenzodiazepines | MERCK & CO. INC. (US) | 1992-11-19 | — | — | EP | disclosed |