Ether

Ether

SCHEMBL9470295

CCOCC.O/N=C\CCOc1ccc(Cc2cccc(F)c2)cc1Cl

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
MAPT P10636 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
LTA4H P09960 1/20 0.39
ATM Q13315 1/20 0.38
CSNK2A1 P68400 2/20 0.38
SMN1; SMN2 Q16637 3/20 0.36
NPC1 O15118 1/20 0.36
NFKB1 P19838 1/20 0.36
RAB9A P51151 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36
EGFR P00533 7/20 0.36
ERBB2 P04626 7/20 0.36
NTRK1 P04629 1/20 0.36
GLA P06280 1/20 0.35
BACE1 P56817 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL9470311 1.00 CYP1A2 (0.40) CYP1A2CYP3A4CYP2D6MAPTCYP2C9
SCHEMBL9471559 0.94 MAPT (0.44) CYP1A2CYP3A4CYP2D6MAPTCYP2C9
SCHEMBL9471556 0.94 MAPT (0.44) CYP1A2CYP3A4CYP2D6MAPTCYP2C9
Ether SCHEMBL9470947 0.92 CSNK2A1 (0.39) LTA4HATMCSNK2A1SMN1; SMN2GLA
Ether SCHEMBL9470960 0.92 CSNK2A1 (0.39) LTA4HATMCSNK2A1SMN1; SMN2GLA
SCHEMBL9471560 0.90 MAPT (0.43) CYP1A2CYP3A4CYP2D6MAPTCYP2C9
Ether SCHEMBL9470837 0.89 LTA4H (0.49) CYP1A2CYP3A4CYP2D6MAPTCYP2C19
Ether SCHEMBL9470818 0.89 LTA4H (0.49) CYP1A2CYP3A4CYP2D6MAPTCYP2C19
SCHEMBL9470301 0.85 LTA4H (0.40) CYP1A2CYP3A4CYP2D6MAPTCYP2C9
Ether SCHEMBL9471813 0.83 PPARA (0.44) PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5232949-A Insecticides, miticides; potentiation SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-08-03 US claimed
EP-0514831-A2 3-(4-Substituted-2-chlorophenoxy)propionaldoxime ethyl ether compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-11-25 EP claimed
US-5232949-A Insecticides, miticides; potentiation SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-08-03 US disclosed
EP-0514831-A2 3-(4-Substituted-2-chlorophenoxy)propionaldoxime ethyl ether compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-11-25 EP disclosed