Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9469223 | 0.85 | APP (0.60) | APPKCNH2CA12CA1CA2 | |
| SCHEMBL15014228 | 0.84 | APP (0.59) | APPKCNH2CA12CA1CA2 | |
| SCHEMBL14104821 | 0.82 | GRM5 (0.46) | GRM5ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL9469188 | 0.81 | NQO1 (0.50) | GRM5ACACBALDH1A1 | |
| SCHEMBL13657794 | 0.81 | CYP11B1 (0.53) | APPKCNH2ACACBPOLBALDH1A1 | |
| SCHEMBL10300057 | 0.81 | APP (0.77) | APPKCNH2CA12CA1CA2 | |
| SCHEMBL674764 | 0.81 | APP (0.77) | APPKCNH2CA12CA1CA2 | |
| SCHEMBL1478622 | 0.80 | GRM5 (0.55) | GRM5CA12CA1CA2CA9 | |
| SCHEMBL17845089 | 0.80 | APP (0.63) | APPCA1CA2GAA | |
| SCHEMBL27803325 | 0.79 | APP (0.63) | APPKCNH2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5242618-A | Liquid crystals | MERCK PATENT GESELLSCHAFT (DE) | 1993-09-07 | — | — | US | disclosed |