Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.36 |
| ▸ | PDE4A | P27815 | 3/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.36 |
| ▸ | TLK2 | Q86UE8 | 3/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9469724 | 0.85 | CYP1A2 (0.43) | HPGDSMN1; SMN2L3MBTL1RAB9AALDH1A1 | |
| SCHEMBL6763737 | 0.75 | MAPT (0.50) | HSD17B3HPGDSMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL9484788 | 0.73 | ESR1 (0.48) | HSD17B3HPGDSMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL12266541 | 0.71 | ALDH1A1 (0.69) | HSD17B3HPGDALDH1A1MAPTMEN1 | |
| SCHEMBL10803052 | 0.71 | KDM4E (0.50) | HSD17B3HPGDSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL9470120 | 0.71 | HSD17B3 (0.44) | HSD17B3HPGDSMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL17297936 | 0.70 | KDM4E (0.47) | HSD17B3HPGDSMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL26254861 | 0.69 | HSD17B3 (0.82) | HSD17B3HPGDSMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL11293674 | 0.69 | NPSR1 (0.51) | HSD17B3HPGDSMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL26958041 | 0.68 | HSD17B3 (0.61) | HSD17B3HPGDSMN1; SMN2L3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5246951-A | Nonsteroidal antiinflammatory agents | ADIR ET COMPAGNIE (FR) | 1993-09-21 | — | — | US | disclosed |
| EP-0487423-A1 | Benzoselenazolinone derivatives, their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-05-27 | — | — | EP | disclosed |