SCHEMBL9470591

SCHEMBL9470591

CCOc1ccc(C#Cc2cc(F)c(F)c(F)c2)cc1

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.50
ACACB O00763 17/20 0.43
LTA4H P09960 1/20 0.43
TSHR P16473 1/20 0.42
TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9469465 0.86 LTA4H (0.46) ACACBLTA4HTSHR
SCHEMBL9470588 0.86 LTA4H (0.46) ACACBLTA4H
SCHEMBL9469188 0.86 NQO1 (0.50) NQO1ACACBTSHRTDP1
SCHEMBL9470198 0.83 NR5A1 (0.51) ACACBLTA4HTSHR
SCHEMBL31160399 0.82 NQO1 (0.74) NQO1ACACBLTA4HTSHRTDP1
SCHEMBL9470334 0.82 NR5A1 (0.54) LTA4HTSHR
SCHEMBL9469759 0.82 NR5A1 (0.54) LTA4HTSHR
SCHEMBL9470514 0.82 NR5A1 (0.54) LTA4HTSHR
SCHEMBL9470079 0.82 NR5A1 (0.54) LTA4HTSHR
SCHEMBL9469223 0.81 APP (0.60) ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5242618-A Liquid crystals MERCK PATENT GESELLSCHAFT (DE) 1993-09-07 US disclosed