Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 6/20 | 0.55 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9313307 | 0.91 | AHCY (0.52) | AHCYNT5EHDAC6HDAC1HDAC4 | |
| SCHEMBL9310980 | 0.88 | AHCY (0.50) | AHCYNT5ENR1I2ALBPDE4D | |
| SCHEMBL9309144 | 0.87 | AHCY (0.65) | AHCYNT5EADORA2BPDE4DLMNA | |
| SCHEMBL9311466 | 0.87 | AHCY (0.54) | AHCYNT5EHDAC6HDAC1HDAC4 | |
| SCHEMBL10513750 | 0.85 | AHCY (0.72) | AHCYNT5EADORA2BLMNATP53 | |
| SCHEMBL10380515 | 0.85 | AHCY (0.59) | AHCYNT5EHDAC6HDAC1HDAC4 | |
| SCHEMBL10513742 | 0.85 | AHCY (0.72) | AHCYNT5EADORA2BLMNATP53 | |
| SCHEMBL10448253 | 0.85 | AHCY (0.59) | AHCYNT5EHDAC6HDAC1HDAC4 | |
| SCHEMBL8537046 | 0.85 | AHCY (0.59) | AHCYNT5EHDAC6HDAC1HDAC4 | |
| SCHEMBL8537042 | 0.85 | AHCY (0.59) | AHCYNT5EHDAC6HDAC1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5246931-A | Triazine-substituted cyclobutane derivatives; viricides; side effect reduction | BRISTOL-MYERS SQUIBB COMPANY (US) | 1993-09-21 | — | — | US | disclosed |
| US-5153352-A | Viricides and antitumor agent | BRISTOL-MYERS SQUIBB COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0366059-A2 | Carbocyclic nucleoside analogs | BRISTOL-MYERS SQUIBB COMPANY (US) | 1990-05-02 | — | — | EP | disclosed |