SCHEMBL9470730

SCHEMBL9470730

O=C(NC1CC(O)C1)OCc1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.65
GAA P10253 1/20 0.65
TSHR P16473 1/20 0.62
EPHX1 P07099 1/20 0.58
CTSL P07711 1/20 0.55
CTSB P07858 1/20 0.55
CTSK P43235 1/20 0.55
TLR4 O00206 1/20 0.54
CPB1 P15086 2/20 0.52
CA12 O43570 1/20 0.51
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
CA9 Q16790 1/20 0.51
HSD11B1 P28845 1/20 0.50
KDM1A O60341 1/20 0.50
MAOB P27338 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15221619 1.00 ALDH1A1 (0.65) ALDH1A1GAATSHREPHX1CTSL
SCHEMBL15221598 1.00 ALDH1A1 (0.65) ALDH1A1GAATSHREPHX1CTSL
SCHEMBL22042442 0.93 ALDH1A1 (0.69) ALDH1A1GAATSHREPHX1CTSL
SCHEMBL22042390 0.93 ALDH1A1 (0.69) ALDH1A1GAATSHREPHX1CTSL
SCHEMBL22042394 0.93 ALDH1A1 (0.69) ALDH1A1GAATSHREPHX1CTSL
SCHEMBL8548058 0.91 ALDH1A1 (0.65) ALDH1A1GAATSHREPHX1CTSL
SCHEMBL6807313 0.91 ALDH1A1 (0.65) ALDH1A1GAATSHREPHX1CTSL
SCHEMBL2621442 0.91 ALDH1A1 (0.65) ALDH1A1GAATSHREPHX1CTSL
SCHEMBL15428355 0.91 ALDH1A1 (0.65) ALDH1A1GAATSHREPHX1CTSL
SCHEMBL10188288 0.91 ALDH1A1 (0.65) ALDH1A1GAATSHREPHX1CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025108255-A1 POLYCYCLIC DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海齐鲁制药研究中心有限公司 2025-05-30 WO disclosed
WO-2025106362-A1 RIPK1 INHIBITORS AND METHODS OF USE MERCK SHARP & DOHME LLC (US) 2025-05-22 WO disclosed
US-20230257720-A1 KETOREDUCTASE MUTANT AND APPLICATIONS THEREOF ASYMCHEM LIFE SCIENCE (TIANJIN) CO., LTD. (CN) 2023-08-17 US disclosed
US-20230257720-A1 KETOREDUCTASE MUTANT AND APPLICATIONS THEREOF ASYMCHEM LIFE SCIENCE (TIANJIN) CO., LTD. (CN) 2023-08-17 US disclosed
US-5246931-A Triazine-substituted cyclobutane derivatives; viricides; side effect reduction BRISTOL-MYERS SQUIBB COMPANY (US) 1993-09-21 US disclosed
US-5153352-A Viricides and antitumor agent BRISTOL-MYERS SQUIBB COMPANY (US) 1992-10-06 US disclosed
EP-0366059-A2 Carbocyclic nucleoside analogs BRISTOL-MYERS SQUIBB COMPANY (US) 1990-05-02 EP disclosed