SCHEMBL9470786

SCHEMBL9470786

CC(=O)Nc1ccccc1C(=O)O.[PbH2]

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.70
POLB P06746 2/20 0.70
NPC1 O15118 3/20 0.67
RAB9A P51151 3/20 0.67
SMN1; SMN2 Q16637 2/20 0.67
KMT2A Q03164 2/20 0.59
MASP2 O00187 1/20 0.59
DHODH Q02127 2/20 0.58
TRPM8 Q7Z2W7 1/20 0.58
ALDH1A1 P00352 1/20 0.57
HPGD P15428 1/20 0.57
KDM4E B2RXH2 2/20 0.56
MEN1 O00255 1/20 0.56
PKM P14618 1/20 0.56
HSD17B10 Q99714 1/20 0.56
ABCC1 P33527 1/20 0.54
CFD P00746 1/20 0.53
CA12 O43570 1/20 0.53
CA2 P00918 1/20 0.53
CA9 Q16790 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27819891 0.98 POLB (0.72) CYP2C19POLBNPC1RAB9ASMN1; SMN2
SCHEMBL110042 0.98 POLB (0.72) CYP2C19POLBNPC1RAB9ASMN1; SMN2
SCHEMBL29437050 0.98 POLB (0.72) CYP2C19POLBNPC1RAB9ASMN1; SMN2
Acetic Acid SCHEMBL27630031 0.96 POLB (0.70) CYP2C19POLBNPC1RAB9ASMN1; SMN2
SCHEMBL11055851 0.96 POLB (0.70) CYP2C19POLBNPC1RAB9ASMN1; SMN2
SCHEMBL27437840 0.96 POLB (0.70) CYP2C19POLBNPC1RAB9ASMN1; SMN2
Hydrochloric Acid SCHEMBL554585 0.96 POLB (0.70) CYP2C19POLBNPC1RAB9ASMN1; SMN2
Hydroxyamine SCHEMBL4368974 0.94 POLB (0.68) CYP2C19POLBNPC1RAB9ASMN1; SMN2
SCHEMBL14855966 0.91 POLB (0.64) CYP2C19POLBNPC1RAB9ASMN1; SMN2
SCHEMBL10456498 0.88 POLB (0.60) CYP2C19POLBNPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3954533-A NITROCELLULOSE, NITROGLYCERIN AND BALLISTIC MODIFIERS OF LEAD- AND COPPER- SALTS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1976-05-04 US claimed
US-5205983-A Mixture of sorbitol polynitrates and polyolpolynitrates THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1993-04-27 US disclosed