Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MASP2 | O00187 | 1/20 | 0.57 |
| ▸ | DHODH | Q02127 | 2/20 | 0.57 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 1/20 | 0.53 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.53 |
| ▸ | CFD | P00746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL110042 | 0.96 | POLB (0.72) | POLBCYP2C19NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27819891 | 0.96 | POLB (0.72) | POLBCYP2C19NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29437050 | 0.96 | POLB (0.72) | POLBCYP2C19NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27437840 | 0.94 | POLB (0.70) | POLBCYP2C19NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11055851 | 0.94 | POLB (0.70) | POLBCYP2C19NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL554585 | 0.94 | POLB (0.70) | POLBCYP2C19NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9470786 | 0.94 | CYP2C19 (0.70) | POLBCYP2C19NPC1RAB9ASMN1; SMN2 | |
| Acetic Acid SCHEMBL27630031 | 0.94 | POLB (0.70) | POLBCYP2C19NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14855966 | 0.89 | POLB (0.64) | POLBCYP2C19NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10456498 | 0.86 | POLB (0.60) | POLBCYP2C19NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7585850-B2 | Stable and active complexes of adenosine and adenosine phosphates with aminoalcohols for the treatment of pulmonary artery hypertension, cardiac failure and other diseases | ADENOBIO N.V. (NL) | 2009-09-08 | — | — | US | disclosed |
| US-20050176675-A1 | Stable and active complexes of adenosine and adenosine phosphates with aminoalcohols for the treatment of pulmonary artery hypertension, cardiac failure and other diseases | ADENOBIO N.V. (NL) | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176675-A1 | Stable and active complexes of adenosine and adenosine phosphates with aminoalcohols for the treatment of pulmonary artery hypertension, cardiac failure and other diseases | ADK, ADORA3, ADORA1 | POLB 866/4885CYP2C19 2410/4885NPC1 2889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.