Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | CASP6 | P55212 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8087903 | 0.88 | HSD17B10 (0.40) | HSD17B10RAPGEF4ALDH1A1TDP1KDM4E | |
| SCHEMBL8086619 | 0.84 | HSD17B10 (0.41) | HSD17B10RAPGEF4ALDH1A1TDP1KDM4E | |
| SCHEMBL10477944 | 0.80 | HSD17B10 (0.44) | HSD17B10RAPGEF4ALDH1A1TDP1KDM4E | |
| SCHEMBL9138757 | 0.80 | HSD17B10 (0.39) | HSD17B10RAPGEF4ALDH1A1TDP1KDM4E | |
| SCHEMBL156095 | 0.79 | HSD17B10 (0.49) | HSD17B10RAPGEF4ALDH1A1TDP1KDM4E | |
| SCHEMBL8164591 | 0.79 | HSD17B10 (0.45) | HSD17B10RAPGEF4ALDH1A1TDP1KDM4E | |
| SCHEMBL9812902 | 0.79 | HSD17B10 (0.45) | HSD17B10RAPGEF4ALDH1A1TDP1KDM4E | |
| SCHEMBL9471236 | 0.77 | TDP1 (0.40) | ALDH1A1TDP1KDM4EPOLBMAPT | |
| Hydrochloric Acid SCHEMBL9812898 | 0.77 | HSD17B10 (0.44) | HSD17B10RAPGEF4ALDH1A1TDP1KDM4E | |
| SCHEMBL1606275 | 0.77 | MAPT (0.57) | HSD17B10RAPGEF4ALDH1A1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5256774-A | Bifunctional reactive dyestuffs containing the 2-(N-substituted amino)-4-(N-phenylamino)-1,3,5-trlazinyl moiety | BAYER AKTIENGESELLSCHAFT (DE) | 1993-10-26 | — | — | US | disclosed |