Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 3/20 | 0.41 |
| ▸ | CASP6 | P55212 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NSD2 | O96028 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8164591 | 0.87 | HSD17B10 (0.45) | HSD17B10RAPGEF4ALDH1A1POLBGAA | |
| SCHEMBL8086619 | 0.87 | HSD17B10 (0.41) | HSD17B10RAPGEF4ALDH1A1POLBGAA | |
| Hydrochloric Acid SCHEMBL9812898 | 0.86 | HSD17B10 (0.44) | HSD17B10RAPGEF4ALDH1A1POLBGAA | |
| SCHEMBL1606275 | 0.86 | MAPT (0.57) | HSD17B10RAPGEF4ALDH1A1POLBGAA | |
| SCHEMBL10477944 | 0.86 | HSD17B10 (0.44) | HSD17B10RAPGEF4ALDH1A1POLBGAA | |
| SCHEMBL8087903 | 0.86 | HSD17B10 (0.40) | HSD17B10RAPGEF4ALDH1A1POLBGAA | |
| SCHEMBL156095 | 0.84 | HSD17B10 (0.49) | HSD17B10RAPGEF4ALDH1A1POLBGAA | |
| SCHEMBL10788421 | 0.84 | HSD17B10 (0.46) | HSD17B10RAPGEF4ALDH1A1POLBGAA | |
| SCHEMBL10581528 | 0.84 | CA2 (0.43) | HSD17B10RAPGEF4ALDH1A1POLBGAA | |
| SCHEMBL11111265 | 0.83 | HSD17B10 (0.45) | HSD17B10RAPGEF4ALDH1A1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299328-B1 | REACTIVE DYES | BAYER AG (DE) | 1991-07-10 | — | — | EP | disclosed |
| EP-0299328-A2 | Reactive dyes | BAYER AG (DE) | 1989-01-18 | — | — | EP | disclosed |