SCHEMBL9470951

SCHEMBL9470951

CCON=CCCOc1ccc(Cc2cc(F)cc(F)c2)cc1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 2/20 0.40
SMN1; SMN2 Q16637 3/20 0.38
GLA P06280 1/20 0.38
LTA4H P09960 1/20 0.37
BACE1 P56817 1/20 0.34
LMNA P02545 1/20 0.34
PPARA Q07869 4/20 0.34
EGFR P00533 1/20 0.34
ATM Q13315 2/20 0.34
RAB9A P51151 2/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
TP53 P04637 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPT P10636 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
S1PR2 O95136 1/20 0.33
S1PR1 P21453 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9470955 0.95 CSNK2A1 (0.40) CSNK2A1SMN1; SMN2GLALTA4HBACE1
SCHEMBL9470301 0.91 LTA4H (0.40) CSNK2A1SMN1; SMN2GLALTA4HEGFR
SCHEMBL9470307 0.87 LTA4H (0.40) CSNK2A1SMN1; SMN2GLALTA4HBACE1
SCHEMBL9470824 0.86 LTA4H (0.51) CSNK2A1SMN1; SMN2GLALTA4HBACE1
Ether SCHEMBL9470960 0.84 CSNK2A1 (0.39) CSNK2A1SMN1; SMN2GLALTA4HBACE1
Ether SCHEMBL9470947 0.84 CSNK2A1 (0.39) CSNK2A1SMN1; SMN2GLALTA4HBACE1
SCHEMBL9471727 0.82 PPARA (0.41) PPARAPPARD
SCHEMBL9470832 0.81 LTA4H (0.51) CSNK2A1SMN1; SMN2GLALTA4HBACE1
SCHEMBL9470859 0.80 LTA4H (0.42) CSNK2A1SMN1; SMN2GLALTA4HPPARA
SCHEMBL9471728 0.77 PPARA (0.43) PPARAATMRAB9AMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5232949-A Insecticides, miticides; potentiation SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-08-03 US claimed
EP-0514831-A2 3-(4-Substituted-2-chlorophenoxy)propionaldoxime ethyl ether compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-11-25 EP claimed
US-5232949-A Insecticides, miticides; potentiation SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-08-03 US disclosed
EP-0514831-A2 3-(4-Substituted-2-chlorophenoxy)propionaldoxime ethyl ether compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-11-25 EP disclosed