SCHEMBL9470982

SCHEMBL9470982

ON=CCCOc1ccc(Oc2cc(F)cc(F)c2)cc1Cl

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 17/20 0.44
PPARG P37231 7/20 0.44
PPARD Q03181 11/20 0.43
NPC1 O15118 1/20 0.36
MAPT P10636 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MRGPRX4 Q96LA9 1/20 0.35
FFAR1 O14842 1/20 0.35
FFAR4 Q5NUL3 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9470975 1.00 PPARA (0.44) PPARAPPARGPPARDNPC1MAPT
SCHEMBL9470988 0.94 PPARA (0.46) PPARAPPARGPPARDNPC1MAPT
Ether SCHEMBL9471722 0.93 PPARA (0.42) PPARAPPARGPPARDNPC1MAPT
Ether SCHEMBL9471730 0.93 PPARA (0.42) PPARAPPARGPPARDNPC1MAPT
Ether SCHEMBL9471813 0.84 PPARA (0.44) PPARAPPARGPPARDFFAR1FFAR4
Ether SCHEMBL9471796 0.84 PPARA (0.44) PPARAPPARGPPARDFFAR1FFAR4
SCHEMBL9471727 0.83 PPARA (0.41) PPARAPPARGPPARD
SCHEMBL9471654 0.83 PPARA (0.46) PPARAPPARGPPARDMRGPRX4
SCHEMBL9471728 0.79 PPARA (0.43) PPARAPPARGPPARDMAPTRAB9A
SCHEMBL8959080 0.79 PPARA (0.46) PPARAPPARGPPARDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5232949-A Insecticides, miticides; potentiation SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-08-03 US disclosed
EP-0514831-A2 3-(4-Substituted-2-chlorophenoxy)propionaldoxime ethyl ether compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-11-25 EP disclosed