SCHEMBL8959080

SCHEMBL8959080

NCCOc1ccc(Oc2cc(F)cc(F)c2)cc1Cl

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 14/20 0.46
PPARG P37231 4/20 0.46
PPARD Q03181 10/20 0.46
GLA P06280 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CSNK2A1 P68400 2/20 0.40
HTR2A P28223 1/20 0.39
SLC6A4 P31645 1/20 0.39
KCNH2 Q12809 1/20 0.39
LTA4H P09960 1/20 0.39
PLA2G2A P14555 1/20 0.39
SOS1 Q07889 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8959084 0.90 PPARA (0.56) PPARAPPARGPPARDGLASMN1; SMN2
SCHEMBL8959126 0.89 PPARA (0.48) PPARAPPARGPPARDGLASMN1; SMN2
SCHEMBL8959125 0.88 LTA4H (0.39) PPARAPPARGPPARDGLASMN1; SMN2
SCHEMBL8959114 0.84 HTR2A (0.47) PPARAPPARGPPARDGLASMN1; SMN2
SCHEMBL9459574 0.84 PPARA (0.48) PPARAPPARGPPARDHTR2ASLC6A4
SCHEMBL8959091 0.83 LTA4H (0.46) PPARAPPARGPPARDGLASMN1; SMN2
SCHEMBL8958988 0.83 MPO (0.36) GLASMN1; SMN2CSNK2A1HTR2ALTA4H
SCHEMBL9306730 0.82 LTA4H (0.39) SMN1; SMN2LTA4HPLA2G2A
SCHEMBL8959117 0.82 LTA4H (0.62) PPARAPPARGPPARDGLASMN1; SMN2
SCHEMBL9471654 0.82 PPARA (0.46) PPARAPPARGPPARDHTR2ASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0514833-B1 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL CO (JP) 1996-01-17 EP disclosed
EP-0460472-B1 Carbamic acid derivatives, their production and use SUMITOMO CHEMICAL CO (JP) 1995-03-08 EP disclosed
US-5364966-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-11-15 US disclosed
US-5356930-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-10-18 US disclosed
US-5346920-A Insecticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-09-13 US disclosed
EP-0514833-A2 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-11-25 EP disclosed
EP-0460472-A1 Carbamic acid derivatives, their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-12-11 EP disclosed