Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY5 | O95622 | 6/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.39 |
| ▸ | AHCY | P23526 | 2/20 | 0.38 |
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 3/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685305 | 0.79 | ADCY5 (0.48) | ADCY5ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL9685291 | 0.77 | ADCY5 (0.48) | ADCY5ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL9469908 | 0.76 | ADORA2A (0.46) | ADORA2AAHCYTYMPPI4KAPI4K2B | |
| SCHEMBL10475247 | 0.75 | ADCY5 (0.55) | ADCY5ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL24196376 | 0.75 | ADORA2A (0.65) | ADCY5ADORA2API4KAPI4K2BPI4K2A | |
| Hydrochloric Acid SCHEMBL31591398 | 0.74 | ADORA2A (0.49) | ADCY5ADORA2AAHCYPI4KAPI4K2B | |
| SCHEMBL20691939 | 0.74 | P2RY1 (0.40) | ADCY5P2RY1 | |
| SCHEMBL20691971 | 0.73 | ADCY5 (0.35) | ADCY5ADORA2ATYMPPI4KAPI4K2B | |
| SCHEMBL9786770 | 0.72 | ADORA2A (0.49) | ADCY5ADORA2ATYMPPI4KAPI4K2B | |
| SCHEMBL20691937 | 0.72 | P2RY1 (0.36) | ADCY5TYMPP2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5246931-A | Triazine-substituted cyclobutane derivatives; viricides; side effect reduction | BRISTOL-MYERS SQUIBB COMPANY (US) | 1993-09-21 | — | — | US | disclosed |
| US-5153352-A | Viricides and antitumor agent | BRISTOL-MYERS SQUIBB COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0366059-A2 | Carbocyclic nucleoside analogs | BRISTOL-MYERS SQUIBB COMPANY (US) | 1990-05-02 | — | — | EP | disclosed |