Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 2/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | POLA1 | P09884 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12547207 | 1.00 | KARS1 (0.47) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL2603440 | 1.00 | KARS1 (0.47) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL19924625 | 0.87 | CYP3A4 (0.49) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL23188046 | 0.82 | CYP3A4 (0.37) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL16902970 | 0.80 | NR1H2 (0.37) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL17429269 | 0.79 | NR1H2 (0.36) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL17429276 | 0.78 | NR1H2 (0.37) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL17429271 | 0.78 | NR1H2 (0.36) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL17429272 | 0.78 | NR1H2 (0.37) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL17429273 | 0.77 | NR1H2 (0.36) | KARS1RXRACCNE1CDK2RXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5248696-A | Abietanoic acid derivatives | WORLD RESEARCH INSTITUTE FOR SCIENCE AND TECHNOLOGY, INC. (US) | 1993-09-28 | — | — | US | claimed |
| WO-1992018119-A1 | COMPOSITION AND METHOD FOR TREATING TUMORS | WORLD RESEARCH INSTITUTE FOR SCIENCE AND TECHNOLOGY, INC. (US) | 1992-10-29 | — | — | WO | claimed |
| US-5248696-A | Abietanoic acid derivatives | WORLD RESEARCH INSTITUTE FOR SCIENCE AND TECHNOLOGY, INC. (US) | 1993-09-28 | — | — | US | disclosed |
| WO-1992018119-A1 | COMPOSITION AND METHOD FOR TREATING TUMORS | WORLD RESEARCH INSTITUTE FOR SCIENCE AND TECHNOLOGY, INC. (US) | 1992-10-29 | — | — | WO | disclosed |