Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10879140 | 0.90 | MAPK1 (0.42) | MAPK1KMT2ANOD2ALDH1A1THRB | |
| SCHEMBL9473759 | 0.88 | MAPK1 (0.38) | MAPK1KMT2AALDH1A1THRBCA1 | |
| SCHEMBL10907607 | 0.85 | MAPK1 (0.40) | MAPK1 | |
| SCHEMBL7566969 | 0.80 | KMT2A (0.37) | MAPK1KMT2ACA1CA2CA9 | |
| SCHEMBL9473154 | 0.79 | L3MBTL1 (0.53) | MAPK1KMT2AALDH1A1 | |
| SCHEMBL16367194 | 0.78 | KMT2A (0.47) | MAPK1KMT2AALDH1A1CA1CA2 | |
| SCHEMBL8823006 | 0.78 | KMT2A (0.47) | MAPK1KMT2AALDH1A1CA1CA2 | |
| SCHEMBL2503399 | 0.78 | KMT2A (0.47) | MAPK1KMT2AALDH1A1CA1CA2 | |
| SCHEMBL12391259 | 0.78 | KMT2A (0.47) | MAPK1KMT2AALDH1A1CA1CA2 | |
| SCHEMBL16864092 | 0.78 | KMT2A (0.47) | MAPK1KMT2AALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264431-A | Inhibitors for proteinkinase C | CIBA-GEIGY CORP. (US) | 1993-11-23 | — | — | US | disclosed |
| US-4548923-A | IMMUNOSTIMULANTS, BACTERICIDES, VIRICIDES | CIBA GEIGY CORPORATION (US) | 1985-10-22 | — | — | US | disclosed |
| US-4406889-A | IMMUNOLOGY, PEPTIDES | CIBA-GEIGY CORPORATION (US) | 1983-09-27 | — | — | US | disclosed |