SCHEMBL9474200

SCHEMBL9474200

O=C1c2ccccc2C(=C2c3ccccc3Oc3c(Cl)cccc32)c2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 4/20 0.49
MEN1 O00255 1/20 0.39
CDC25B P30305 1/20 0.39
KMT2A Q03164 1/20 0.39
DNMT1 P26358 2/20 0.38
IDO1 P14902 1/20 0.38
DNMT3L Q9UJW3 1/20 0.38
DNMT3A Q9Y6K1 1/20 0.38
MAOB P27338 2/20 0.38
MAOA P21397 1/20 0.38
PKM P14618 1/20 0.37
TSHR P16473 1/20 0.37
PTPRC P08575 1/20 0.37
STK17B O94768 1/20 0.35
ELANE P08246 2/20 0.35
NSD2 O96028 1/20 0.34
BCHE P06276 1/20 0.34
DAO P14920 1/20 0.34
CES1 P23141 1/20 0.34
HSP90AA1 P07900 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL302326 0.80 MEN1 (0.55) MEN1CDC25BKMT2ADNMT1IDO1
SCHEMBL9474311 0.74 S100A4 (0.56) MEN1CDC25BKMT2ADNMT1IDO1
SCHEMBL8134709 0.70 MAPT (0.49) AHRMEN1KMT2AMAOBMAOA
SCHEMBL769933 0.70 MEN1 (0.80) MEN1CDC25BKMT2ADNMT1IDO1
SCHEMBL29402128 0.70 MEN1 (0.80) MEN1CDC25BKMT2ADNMT1IDO1
SCHEMBL19591719 0.69 AHR (0.55) AHRHRH4
SCHEMBL9475303 0.68 ELANE (0.62) MEN1CDC25BKMT2AMAOBMAOA
SCHEMBL9579668 0.68
SCHEMBL29406907 0.67 MAPK1 (0.52) AHRMAOBMAOAPKMTSHR
SCHEMBL302174 0.67 MAPK1 (0.52) AHRMAOBMAOAPKMTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5239338-A Storage apparatus comprising a plurality of layers PEARSON ROBERT E (US) 1993-08-24 US disclosed
US-5099270-A Storage apparatus comprising a plurality of layers Secrest, Thomas W. (US) 1992-03-24 US disclosed
US-4845529-A Storage apparatus comprising a plurality of layers THOMAS W. SECREST (US) 1989-07-04 US disclosed
US-4199359-A Photographic screen stencil printing process XEROX CORPORATION (US) 1980-04-22 US disclosed