Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | ACR | P10323 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20931321 | 0.91 | MAPT (0.55) | FFAR1MAPTKMT2APRSS1ACR | |
| SCHEMBL9473529 | 0.91 | FFAR1 (0.45) | FFAR1MAPTKMT2APRSS1ACR | |
| SCHEMBL9473940 | 0.87 | PRSS1 (0.48) | MAPTKMT2APRSS1ACRLMNA | |
| SCHEMBL10476847 | 0.86 | NPC1 (0.50) | FFAR1MAPTKMT2APRSS1ACR | |
| SCHEMBL9473430 | 0.86 | NPC1 (0.50) | FFAR1MAPTKMT2APRSS1ACR | |
| SCHEMBL9638787 | 0.86 | MAPT (0.50) | FFAR1MAPTKMT2APRSS1ACR | |
| SCHEMBL6936519 | 0.86 | MAPT (0.50) | FFAR1MAPTKMT2APRSS1ACR | |
| SCHEMBL12154317 | 0.86 | MAPT (0.50) | FFAR1MAPTKMT2APRSS1ACR | |
| SCHEMBL9474183 | 0.85 | LMNA (0.51) | MAPTKMT2APRSS1ACRLMNA | |
| SCHEMBL9475821 | 0.85 | LMNA (0.51) | MAPTKMT2APRSS1ACRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250222-A | Optically active compounds used for liquid crystalline mixtures | HOFFMANN-LA ROCHE INC. (US) | 1993-10-05 | — | — | US | disclosed |