Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.53 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL947456 | 1.00 | S1PR1 (0.53) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL954320 | 0.87 | S1PR1 (0.56) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL946726 | 0.87 | S1PR1 (0.56) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL945112 | 0.85 | S1PR1 (0.72) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL946486 | 0.80 | S1PR1 (0.64) | S1PR1S1PR5S1PR4 | |
| SCHEMBL945527 | 0.79 | S1PR1 (0.58) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL945528 | 0.79 | S1PR1 (0.58) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL946154 | 0.79 | S1PR1 (0.53) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL950655 | 0.78 | S1PR1 (0.78) | S1PR1S1PR5S1PR4 | |
| SCHEMBL946606 | 0.78 | S1PR1 (0.78) | S1PR1S1PR5S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011005290-A1 | DISUBSTITUTED OXADIAZOLE DERIVATIVES USEFUL IN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS | ARENA PHARMACEUTICALS, INC. (US) | 2011-01-13 | — | — | WO | disclosed |
| WO-2011005290-A1 | DISUBSTITUTED OXADIAZOLE DERIVATIVES USEFUL IN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS | ARENA PHARMACEUTICALS, INC. (US) | 2011-01-13 | — | — | WO | disclosed |