Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 12/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.59 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.59 |
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9135133 | 0.86 | GPBAR1 (0.66) | ALOX5HDAC6GPBAR1CYSLTR1CYSLTR2 | |
| SCHEMBL9137854 | 0.86 | GPBAR1 (0.66) | ALOX5HDAC6GPBAR1CYSLTR1CYSLTR2 | |
| SCHEMBL9137219 | 0.85 | GPBAR1 (0.67) | ALOX5HDAC6GPBAR1CYSLTR1CYSLTR2 | |
| SCHEMBL8870875 | 0.83 | ALOX5 (0.61) | ALOX5HDAC6GPBAR1CYSLTR1CYSLTR2 | |
| Bicarbonate SCHEMBL9374712 | 0.80 | CYSLTR1 (0.72) | ALOX5HDAC6GPBAR1CYSLTR1CYSLTR2 | |
| SCHEMBL9136835 | 0.80 | GPBAR1 (0.57) | ALOX5HDAC6GPBAR1CYSLTR1CYSLTR2 | |
| SCHEMBL9135728 | 0.80 | GPBAR1 (0.57) | ALOX5HDAC6GPBAR1CYSLTR1CYSLTR2 | |
| SCHEMBL9135724 | 0.80 | GPBAR1 (0.57) | ALOX5HDAC6GPBAR1CYSLTR1CYSLTR2 | |
| SCHEMBL9136840 | 0.80 | GPBAR1 (0.57) | ALOX5HDAC6GPBAR1CYSLTR1CYSLTR2 | |
| SCHEMBL10438460 | 0.79 | CYSLTR1 (0.65) | ALOX5HDAC6GPBAR1CYSLTR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192771-A | Lipoxygenase inhibitors as antiinflammatory agents | BAYER AKTIENGESELLSCHAFT (DE) | 1993-03-09 | — | — | US | claimed |