SCHEMBL9475181

SCHEMBL9475181

CCNCC#CCNC(=O)C(O)(c1ccccc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 4/20 0.51
LMNA P02545 4/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
CNR1 P21554 1/20 0.50
CNR2 P34972 1/20 0.50
ALDH1A1 P00352 4/20 0.47
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
POLB P06746 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
GAA P10253 1/20 0.40
HPGD P15428 2/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
PAX8 Q06710 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
CHRM2 P08172 1/20 0.38
CHRM4 P08173 1/20 0.38
CHRM1 P11229 1/20 0.38
CHRM3 P20309 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9473641 0.98 HTT (0.50) HTTLMNAL3MBTL1CNR1CNR2
SCHEMBL9473557 0.88 HTT (0.60) HTTLMNAL3MBTL1CNR1CNR2
SCHEMBL9476163 0.84 CNR1 (0.53) HTTLMNAL3MBTL1CNR1CNR2
SCHEMBL9473362 0.84 CNR1 (0.53) HTTLMNAL3MBTL1CNR1CNR2
SCHEMBL24671951 0.83 HTT (0.60) HTTLMNAL3MBTL1CNR1CNR2
SCHEMBL9474958 0.83 CNR1 (0.51) HTTLMNAL3MBTL1CNR1CNR2
Hydrochloric Acid SCHEMBL9474191 0.83 CNR1 (0.51) HTTLMNAL3MBTL1CNR1CNR2
SCHEMBL9473250 0.81 CNR1 (0.54) HTTLMNAL3MBTL1CNR1CNR2
Hydrochloric Acid SCHEMBL9473156 0.80 CNR1 (0.52) HTTLMNAL3MBTL1CNR1CNR2
SCHEMBL9473846 0.80 ALDH1A1 (0.49) HTTLMNAL3MBTL1CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5066680-A NOVEL SUBSTITUTED-ACETAMIDE COMPOUND AND A PROCESS FOR THE PREPARATION THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1991-11-19 US claimed
EP-0383256-A2 A novel substituted-acetamide compound and a process for the preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1990-08-22 EP claimed
JP-2262548-A None JP disclosed
US-5192779-A Substituted-acetamide compound and a process for the preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-03-09 US disclosed
US-5066680-A NOVEL SUBSTITUTED-ACETAMIDE COMPOUND AND A PROCESS FOR THE PREPARATION THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1991-11-19 US disclosed
JP-H02262548-A NOVEL SUBSTITUTED ACETAMIDE COMPOUND AND ITS PRODUCTION FUJISAWA PHARMACEUT CO LTD 1990-10-25 JP disclosed
EP-0383256-A2 A novel substituted-acetamide compound and a process for the preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1990-08-22 EP disclosed