Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PLA2G2C | Q5R387 | 4/20 | 0.34 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9475314 | 0.95 | PLA2G2C (0.41) | PLA2G2CTSHREPHX1ACHE | |
| SCHEMBL7526952 | 0.85 | ALDH1A1 (0.33) | ALDH1A1PLA2G2CRNASELHPGDSMN1; SMN2 | |
| SCHEMBL9474481 | 0.82 | — | — | |
| SCHEMBL19002186 | 0.81 | — | — | |
| SCHEMBL9474805 | 0.81 | — | — | |
| SCHEMBL9473938 | 0.78 | ALDH1A1 (0.44) | ALDH1A1PLA2G2CRNASELHPGDRECQL | |
| SCHEMBL9475316 | 0.78 | — | — | |
| SCHEMBL7535733 | 0.76 | — | — | |
| Snap (S-Nitroso-N-Acetylpenicillamine) SCHEMBL26048343 | 0.74 | KDM4E (0.33) | ALDH1A1RECQLSMN1; SMN2 | |
| Snap (S-Nitroso-N-Acetylpenicillamine) SCHEMBL26048324 | 0.74 | KDM4E (0.33) | ALDH1A1RECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5187305-A | Vasodilators | GLAXO INC. (US) | 1993-02-16 | — | — | US | claimed |
| US-5187305-A | Vasodilators | GLAXO INC. (US) | 1993-02-16 | — | — | US | disclosed |