Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9478617 | 0.99 | KDM4E (0.36) | KDM4EHPGDKMT2AALDH1A1MAPT | |
| SCHEMBL9476323 | 0.99 | KDM4E (0.36) | KDM4EHPGDKMT2AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL9476909 | 0.99 | KDM4E (0.34) | KDM4EHPGDKMT2AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL9484372 | 0.98 | KDM4E (0.36) | KDM4EHPGDKMT2AALDH1A1MAPT | |
| SCHEMBL9479026 | 0.94 | ALDH1A1 (0.35) | KDM4EHPGDKMT2AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL9478561 | 0.93 | ALDH1A1 (0.37) | KDM4EHPGDKMT2AALDH1A1MAPT | |
| SCHEMBL9476913 | 0.92 | TSHR (0.39) | KDM4EHPGDKMT2AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL9475824 | 0.91 | TSHR (0.41) | KDM4EHPGDKMT2AALDH1A1MAPT | |
| SCHEMBL9476649 | 0.91 | ABCC4 (0.37) | KMT2AALDH1A1MAPTSMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL9475930 | 0.90 | ABCC4 (0.36) | KMT2AALDH1A1MAPTTSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179089-A | Antiallergens, asthma | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1993-01-12 | — | — | US | claimed |
| EP-0486211-A1 | Isoquinoline derivatives | CHINOIN Gyògyszer és Vegyészeti Termékek Gyára RT. (HU) | 1992-05-20 | — | — | EP | claimed |