Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | SCN4A | P35499 | 2/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9722840 | 0.85 | CYP3A4 (0.58) | CYP3A4HSD17B10CYP1A2LMNATP53 | |
| SCHEMBL9185915 | 0.82 | CYP3A4 (0.56) | CYP3A4HSD17B10NPC1RAB9ACYP1A2 | |
| SCHEMBL9475114 | 0.82 | HSD17B10 (0.57) | CYP3A4HSD17B10NPC1RAB9ACYP1A2 | |
| SCHEMBL9474741 | 0.82 | CYP3A4 (0.59) | CYP3A4HSD17B10NPC1RAB9ACYP1A2 | |
| Bromide SCHEMBL9189616 | 0.81 | CYP3A4 (0.55) | CYP3A4HSD17B10NPC1RAB9ACYP1A2 | |
| SCHEMBL9188493 | 0.80 | CYP3A4 (0.54) | CYP3A4HSD17B10NPC1RAB9ACYP1A2 | |
| SCHEMBL9476104 | 0.79 | CYP3A4 (0.52) | CYP3A4HSD17B10NPC1RAB9ACYP1A2 | |
| SCHEMBL21395394 | 0.77 | CYP3A4 (0.57) | CYP3A4HSD17B10NPC1RAB9ACYP1A2 | |
| SCHEMBL28795289 | 0.77 | CYP3A4 (0.60) | CYP3A4HSD17B10RAB9ACYP1A2LMNA | |
| SCHEMBL29803040 | 0.77 | CYP3A4 (0.60) | CYP3A4HSD17B10RAB9ACYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236940-A | Administering for treatment of medical conditions associated with the effects of glutamate; glutamate-induced convulsions; schizophrenia; sleep disorders | RHONE-POULENC SANTE (FR) | 1993-08-17 | — | — | US | disclosed |