Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11347359 | 0.87 | CYP3A4 (0.54) | CYP3A4TDP1CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL9475348 | 0.85 | CYP3A4 (0.54) | CYP3A4TDP1CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL7998251 | 0.84 | CYP3A4 (0.56) | CYP3A4TDP1CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL28795289 | 0.84 | CYP3A4 (0.60) | CYP3A4TDP1CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL29803040 | 0.84 | CYP3A4 (0.60) | CYP3A4TDP1CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL2664863 | 0.83 | HSD17B10 (0.64) | CYP3A4TDP1CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL10971640 | 0.83 | CYP3A4 (0.54) | CYP3A4TDP1CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL11363181 | 0.83 | HSD17B10 (0.64) | CYP3A4TDP1CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL17083730 | 0.82 | CYP3A4 (0.54) | CYP3A4TDP1CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL30189983 | 0.81 | ALDH1A1 (0.53) | CYP3A4TDP1CYP1A2CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120872-A | Textile dyeing | CIBA-GEIGY CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |
| US-4994563-A | Dyeing, printing cellulose, silk, wool, synthetic polyamides; colorfastness | CIBA-GEIGY CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0349486-A2 | Azo dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1990-01-03 | — | — | EP | disclosed |
| US-4826989-A | Process for the preparation of luciferin compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1989-05-02 | — | — | US | disclosed |
| EP-0024525-B1 | Process for the preparation of luciferin and its derivatives | Roche Diagnostics GmbH (DE) | 1982-06-30 | — | — | EP | disclosed |
| EP-0024525-A1 | Process for the preparation of luciferin and its derivatives | Roche Diagnostics GmbH (DE) | 1981-03-11 | — | — | EP | disclosed |
| US-4051084-A | BENZOTHIAZOLE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | disclosed |
| US-4039526-A | PRINTING, POLYACRYLONITRILE, POLYESTERS, POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-02 | — | — | US | disclosed |
| US-3991042-A | Basic azo dyestuffs containing a benzthiazole and a tetrahydroquinoline nucleus | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-09 | — | — | US | disclosed |
| US-3948877-A | POLYACRYLONITRILE, ACID MODIFIED POLYESTERS OR POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-06 | — | — | US | disclosed |