Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9475898 | 0.86 | MAPT (0.46) | MAPTCES1LMNATDP1ALDH1A1 | |
| SCHEMBL9475464 | 0.85 | MAPT (0.47) | MAPTCES1LMNATDP1ALDH1A1 | |
| SCHEMBL9474748 | 0.84 | CES1 (0.38) | MAPTCES1LMNATDP1ALDH1A1 | |
| SCHEMBL9474408 | 0.81 | SMN1; SMN2 (0.40) | MAPTLMNATDP1ALDH1A1HDAC1 | |
| SCHEMBL9474430 | 0.80 | PLK1 (0.44) | LMNATDP1ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL9475657 | 0.80 | CES1 (0.45) | MAPTCES1LMNATDP1ALDH1A1 | |
| SCHEMBL9475925 | 0.79 | MAPT (0.43) | MAPTCES1LMNATDP1ALDH1A1 | |
| SCHEMBL9478519 | 0.78 | KDM4E (0.44) | MAPTTDP1ALDH1A1CYP1A2L3MBTL1 | |
| SCHEMBL9476583 | 0.75 | TP53 (0.50) | RARB | |
| SCHEMBL9476200 | 0.71 | CES1 (0.42) | MAPTCES1LMNATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5243066-A | ALKYL 2-ARYL-2,2-DIALKOXYACETATES, THE PREPARATION THEREOF AND A METHOD OF USING THEM FOR PREPARING ARYLGLYOXYLIC ESTERS | BASF AKTIENGESELLSCHAFT (DE) | 1993-09-07 | — | — | US | disclosed |