Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.60 |
| ▸ | TUBB | P07437 | 1/20 | 0.60 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.60 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.60 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.60 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.60 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.60 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.60 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.60 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.60 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.60 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.60 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.60 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.60 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.60 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.60 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.60 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9477423 | 0.91 | ALDH1A1 (0.56) | KDM4EPOLBTUBB4ATUBBTUBA3C | |
| SCHEMBL8803025 | 0.90 | KDM4E (0.59) | KDM4EPOLBTUBB4ATUBBTUBA3C | |
| SCHEMBL9474713 | 0.90 | ALDH1A1 (0.55) | KDM4EPOLBTUBB4ATUBBTUBA3C | |
| SCHEMBL9473967 | 0.90 | KDM4E (0.62) | KDM4EPOLBTUBB4ATUBBTUBA3C | |
| SCHEMBL9474947 | 0.89 | TOP2A (0.61) | KDM4EPOLBALDH1A1HPGDHSD17B10 | |
| SCHEMBL9790144 | 0.89 | ALDH1A1 (0.54) | KDM4EPOLBTUBB4ATUBBTUBA3C | |
| SCHEMBL9473926 | 0.89 | ALDH1A1 (0.54) | KDM4EPOLBTUBB4ATUBBTUBA3C | |
| SCHEMBL7821381 | 0.88 | KDM4E (0.69) | KDM4EPOLBTUBB4ATUBBTUBA3C | |
| SCHEMBL10695164 | 0.88 | KDM4E (0.47) | KDM4EPOLBTUBB4ATUBBTUBA3C | |
| Hydrochloric Acid SCHEMBL10400523 | 0.87 | KDM4E (0.67) | KDM4EPOLBTUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190955-A | Bactericides, effective against antibiotic resistant germs | BAYER AKTIENGESELLSCHAFT (DE) | 1993-03-02 | — | — | US | disclosed |
| US-5051418-A | Antibacterial 8-cyano-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-24 | — | — | US | disclosed |
| US-4908366-A | Bactericides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-03-13 | — | — | US | disclosed |