Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 16/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.50 |
| ▸ | LOX | P28300 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9473852 | 0.87 | ALOX5 (0.77) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL9374489 | 0.87 | ALOX5 (0.77) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL9474562 | 0.85 | ALOX5 (0.73) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL9372899 | 0.85 | ALOX5 (0.73) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL9474780 | 0.84 | ALOX5 (0.73) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL9380719 | 0.84 | ALOX5 (0.73) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL9473471 | 0.83 | ALOX5 (0.70) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL9474760 | 0.77 | ALOX5 (0.73) | ALOX5 | |
| SCHEMBL9474152 | 0.75 | ALOX5 (1.00) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL16021712 | 0.75 | ALOX5 (0.58) | ALOX5GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185363-A | Administering for treatment of inflammatory diseases | ABBOTT LABORATORIES (US) | 1993-02-09 | — | — | US | disclosed |