Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8687902 | 0.80 | FABP4 (0.44) | KDM4EKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL29139837 | 0.76 | KMT2A (0.37) | APEX1KDM4ECA12CA9KMT2A | |
| SCHEMBL29874749 | 0.71 | KDM4E (0.35) | APEX1KDM4ECA12CA9KMT2A | |
| SCHEMBL8132034 | 0.65 | TSHR (0.45) | APEX1KDM4ECA12CA9KMT2A | |
| SCHEMBL16649247 | 0.64 | HTT (0.32) | KMT2A | |
| SCHEMBL6841570 | 0.63 | HSD17B10 (0.31) | — | |
| SCHEMBL8538224 | 0.62 | — | — | |
| SCHEMBL9618341 | 0.59 | CA12 (0.65) | APEX1KDM4ECA12CA9KMT2A | |
| SCHEMBL13088961 | 0.59 | NOTUM (0.47) | APEX1KDM4ECA12CA9KMT2A | |
| SCHEMBL21085910 | 0.58 | DRD1 (0.37) | KDM4EKMT2APOLBCYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4136177-A | FOR TOPICAL OPHTHALMIC USE, DRUG POTENTIATORS | AMERICAN HOME PRODUCTS CORP. (US) | 1979-01-23 | — | — | US | claimed |
| US-5202355-A | Administering for diabetic neuropathy | TAKASAGO INSTITUTE FOR INTERDISCIPLINARY SCIENCE INC. (US) | 1993-04-13 | — | — | US | disclosed |
| US-4136173-A | VEHICLES FOR OPHTHALMIC DRUGS | AMERICAN HOME PRODUCTS CORP. (US) | 1979-01-23 | — | — | US | disclosed |