SCHEMBL9475980

SCHEMBL9475980

CCOC(=O)C(OC)(OC)c1ccc(OC)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
CYP1A2 P05177 2/20 0.45
CYP3A4 P08684 2/20 0.45
MAPT P10636 2/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
KMT2A Q03164 2/20 0.44
HDAC3 O15379 2/20 0.44
HDAC4 P56524 2/20 0.44
HDAC1 Q13547 2/20 0.44
HDAC7 Q8WUI4 2/20 0.44
HDAC2 Q92769 2/20 0.44
HDAC10 Q969S8 2/20 0.44
HDAC11 Q96DB2 2/20 0.44
HDAC8 Q9BY41 2/20 0.44
HDAC6 Q9UBN7 2/20 0.44
HDAC9 Q9UKV0 2/20 0.44
HDAC5 Q9UQL6 2/20 0.44
GLA P06280 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9475903 0.89 PLK1 (0.46) ALDH1A1CYP1A2CYP3A4KMT2ALMNA
SCHEMBL9476928 0.89 ALDH1A1 (0.48) ALDH1A1L3MBTL1CYP1A2CYP3A4MAPT
SCHEMBL9475499 0.86 PPARA (0.50) ALDH1A1L3MBTL1CYP1A2CYP3A4LMNA
SCHEMBL9475925 0.85 MAPT (0.43) ALDH1A1CYP1A2CYP3A4MAPTCYP2C9
SCHEMBL9475755 0.84 NPC1 (0.51) ALDH1A1MAPTCYP2C9HDAC3LMNA
SCHEMBL27916287 0.83 CES1 (0.56) ALDH1A1MAPTKMT2ARECQLTSHR
SCHEMBL9475911 0.82 MAPT (0.50) ALDH1A1L3MBTL1CYP1A2CYP3A4MAPT
SCHEMBL7387122 0.81 ALDH1A1 (0.50) ALDH1A1L3MBTL1CYP1A2CYP3A4MAPT
SCHEMBL9475612 0.81 TP53 (0.51) MAPK1TSHR
SCHEMBL20325777 0.80 ALDH1A1 (0.56) ALDH1A1L3MBTL1CYP1A2CYP3A4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5243066-A ALKYL 2-ARYL-2,2-DIALKOXYACETATES, THE PREPARATION THEREOF AND A METHOD OF USING THEM FOR PREPARING ARYLGLYOXYLIC ESTERS BASF AKTIENGESELLSCHAFT (DE) 1993-09-07 US disclosed