Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 14/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9478238 | 0.82 | CAPN1 (0.47) | KEAP1FFAR1CA1CA2HDAC2 | |
| SCHEMBL69746 | 0.79 | FFAR1 (0.81) | KEAP1FFAR1FFAR4CA1CA2 | |
| SCHEMBL6132102 | 0.79 | KEAP1 (0.59) | KEAP1FFAR1FFAR4CA1CA2 | |
| SCHEMBL9479945 | 0.77 | KEAP1 (0.57) | KEAP1FFAR1FFAR4CA1CA2 | |
| Hydrochloric Acid SCHEMBL25264643 | 0.77 | FFAR1 (0.77) | KEAP1FFAR1FFAR4CA1CA2 | |
| Phenyl Propionic Acid SCHEMBL28098279 | 0.76 | KEAP1 (0.91) | KEAP1FFAR1FFAR4HDAC3MAPK1 | |
| Phenyl Propionic Acid SCHEMBL27365584 | 0.76 | KEAP1 (0.91) | KEAP1FFAR1FFAR4HDAC3MAPK1 | |
| Phenyl Propionic Acid SCHEMBL29619843 | 0.75 | KEAP1 (1.00) | KEAP1FFAR1FFAR4HDAC3MAPK1 | |
| Phenyl Propionic Acid SCHEMBL13618844 | 0.75 | KEAP1 (1.00) | KEAP1FFAR1FFAR4HDAC3MAPK1 | |
| Phenyl Propionic Acid SCHEMBL3419 | 0.75 | KEAP1 (1.00) | KEAP1FFAR1FFAR4HDAC3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346465-B1 | 1-CARBOXY-1-VYNILOXYIMINOAMINOTHIAZOLE CEPHALOSPORING DERIVATIVES AND PROCESS FOR THEIR PREPARATION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-11 | — | — | EP | disclosed |
| US-5225406-A | Antibiotics | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |
| US-5084453-A | Antibiotics, bactericides | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1992-01-28 | — | — | US | disclosed |
| EP-0346465-A1 | 1-CARBOXY-1-VYNILOXYIMINOAMINOTHIAZOLE CEPHALOSPORING DERIVATIVES AND PROCESS FOR THEIR PREPARATION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-12-20 | — | — | EP | disclosed |