SCHEMBL9477261

SCHEMBL9477261

O=C(OCN1CCCC1=O)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.55
RAB9A P51151 1/20 0.55
RXFP1 Q9HBX9 1/20 0.55
POLB P06746 2/20 0.55
ALDH1A1 P00352 2/20 0.55
HTT P42858 1/20 0.51
MAPT P10636 2/20 0.49
MEN1 O00255 1/20 0.49
RECQL P46063 1/20 0.49
KMT2A Q03164 1/20 0.49
TSHR P16473 1/20 0.47
PKM P14618 1/20 0.46
LMNA P02545 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
CHRNB2 P17787 1/20 0.45
CHRNA5 P30532 1/20 0.45
CHRNA7 P36544 1/20 0.45
CHRNA4 P43681 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29144401 0.77 KMT2A (0.53) POLBALDH1A1HTTKMT2ATSHR
SCHEMBL9653929 0.77 KMT2A (0.67) NPC1RAB9ARXFP1POLBMAPT
SCHEMBL10418997 0.76 HTT (0.63) NPC1RAB9ARXFP1POLBALDH1A1
SCHEMBL9478948 0.76 PTGS2 (0.48) ALDH1A1HTTMEN1KMT2ATSHR
SCHEMBL28191960 0.76 TDP1 (0.52) RAB9AALDH1A1HTTMEN1KMT2A
SCHEMBL14127629 0.75 TDP1 (0.47) NPC1RAB9ARXFP1ALDH1A1MAPT
SCHEMBL8469734 0.74 POLB (0.51) NPC1RAB9APOLBALDH1A1HTT
SCHEMBL8069623 0.74 TSHR (0.50) ALDH1A1HTTKMT2ATSHRLMNA
Benzyl Benzoate SCHEMBL27530883 0.73 KMT2A (0.60) NPC1RAB9ARXFP1ALDH1A1MAPT
SCHEMBL9923062 0.73 HTT (0.46) POLBALDH1A1HTTTSHRPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5206386-A Controlled release N-substituted pyrrolidone esters and process for the use thereof ISP INVESTMENTS INC. (US) 1993-04-27 US disclosed