Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 17/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9476083 | 0.88 | ALOX5 (0.52) | ALOX5EPHX2 | |
| SCHEMBL9476486 | 0.88 | ALOX5 (0.54) | ALOX5EPHX2 | |
| SCHEMBL9189969 | 0.88 | ALOX5 (0.43) | ALOX5CA12CA1CA2CA9 | |
| SCHEMBL9475768 | 0.86 | ALOX5 (0.60) | ALOX5CA12CA1CA2CA9 | |
| SCHEMBL9476861 | 0.86 | ALOX5 (0.50) | ALOX5EPHX2 | |
| SCHEMBL9474961 | 0.86 | ALOX5 (0.50) | ALOX5EPHX2 | |
| SCHEMBL9478541 | 0.85 | ALOX5 (0.51) | ALOX5EPHX2 | |
| SCHEMBL9475469 | 0.85 | ALOX5 (0.53) | ALOX5EPHX2 | |
| SCHEMBL9476421 | 0.85 | ALOX5 (0.51) | ALOX5EPHX2 | |
| SCHEMBL9476102 | 0.82 | ALOX5 (0.61) | ALOX5CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202349-A | Lipoxygenase inhibitors, antiasthatics | GRUENENTHAL GMBH (DE) | 1993-04-13 | — | — | US | disclosed |