SCHEMBL9477406

SCHEMBL9477406

CCCC[C@H]1CC[C@H]([C@H]2CC[C@H](CCC=CF)CC2)CC1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.44
HTT P42858 2/20 0.41
LMNA P02545 1/20 0.41
MAPK1 P28482 1/20 0.41
POLB P06746 1/20 0.36
HPGD P15428 1/20 0.36
MAPT P10636 1/20 0.34
PKM P14618 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9477379 1.00 CYP1A2 (0.44) CYP1A2HTTLMNAMAPK1POLB
SCHEMBL9477372 1.00 CYP1A2 (0.44) CYP1A2HTTLMNAMAPK1POLB
SCHEMBL9477394 1.00 CYP1A2 (0.44) CYP1A2HTTLMNAMAPK1POLB
SCHEMBL9477386 1.00 CYP1A2 (0.44) CYP1A2HTTLMNAMAPK1POLB
SCHEMBL9478102 0.95 CYP1A2 (0.38) CYP1A2HTTLMNAMAPK1POLB
SCHEMBL9478108 0.95 CYP1A2 (0.38) CYP1A2HTTLMNAMAPK1POLB
SCHEMBL9478132 0.95 CYP1A2 (0.38) CYP1A2HTTLMNAMAPK1POLB
SCHEMBL9478116 0.95 CYP1A2 (0.38) CYP1A2HTTLMNAMAPK1POLB
SCHEMBL9478125 0.95 CYP1A2 (0.38) CYP1A2HTTLMNAMAPK1POLB
SCHEMBL9475460 0.93 HTT (0.38) CYP1A2HTTLMNAMAPK1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0377469-B1 A LIQUID CRYSTALLINE COMPOUND CHISSO CORPORATION (JP) 1993-10-06 EP disclosed
US-5183587-A LIQUID CRYSTALLINE COMPOUND CHISSO CORPORATION (JP) 1993-02-02 US disclosed
EP-0377469-A1 A liquid crystalline compound CHISSO CORPORATION (JP) 1990-07-11 EP disclosed