Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9477612 | 1.00 | POLB (0.35) | POLBUSP2HTTL3MBTL1CHRM1 | |
| SCHEMBL9478624 | 0.86 | HTT (0.41) | POLBUSP2HTTL3MBTL1TSHR | |
| SCHEMBL9478620 | 0.86 | HTT (0.41) | POLBUSP2HTTL3MBTL1TSHR | |
| SCHEMBL12654920 | 0.82 | POLB (0.38) | POLBHTTCHRM1ALDH1A1TSHR | |
| SCHEMBL9727365 | 0.82 | POLB (0.44) | POLBUSP2HTTL3MBTL1CHRM1 | |
| SCHEMBL9478444 | 0.80 | CHRM1 (0.37) | POLBUSP2HTTL3MBTL1CHRM1 | |
| SCHEMBL9478449 | 0.80 | CHRM1 (0.37) | POLBUSP2HTTL3MBTL1CHRM1 | |
| SCHEMBL7687650 | 0.78 | CHRM1 (0.40) | POLBCHRM1KDM4EMEN1KMT2A | |
| SCHEMBL9031064 | 0.77 | POLB (0.44) | POLBHTTCHRM1KMT2ATSHR | |
| SCHEMBL9224359 | 0.77 | POLB (0.43) | POLBHTTCHRM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5232898-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1993-08-03 | — | — | US | disclosed |