Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9031064 | 0.91 | POLB (0.44) | POLBHTTCHRM1PLK1TSHR | |
| SCHEMBL9478444 | 0.88 | CHRM1 (0.37) | POLBHTTUSP2CHRM1L3MBTL1 | |
| SCHEMBL9478449 | 0.88 | CHRM1 (0.37) | POLBHTTUSP2CHRM1L3MBTL1 | |
| SCHEMBL9224359 | 0.86 | POLB (0.43) | POLBHTTCHRM1PLK1TSHR | |
| SCHEMBL10844388 | 0.86 | POLB (0.38) | POLBHTTUSP2CHRM1L3MBTL1 | |
| SCHEMBL7687650 | 0.83 | CHRM1 (0.40) | POLBCHRM1TSHR | |
| SCHEMBL9345399 | 0.83 | POLB (0.37) | POLBCHRM1PLK1 | |
| SCHEMBL9228447 | 0.82 | POLB (0.44) | POLBCHRM1PLK1TSHRALDH1A1 | |
| SCHEMBL1802016 | 0.82 | ALDH1A1 (0.37) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9477612 | 0.82 | POLB (0.35) | POLBHTTUSP2CHRM1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5127935-A | Halogen, phenyl and heterocycle substituents, agricultural use | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| US-5084084-A | Uracil and thiouracil derivatives | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-01-28 | — | — | US | disclosed |
| EP-0408382-A2 | Uracil derivatives and herbicides containing the same as active ingredient | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1991-01-16 | — | — | EP | disclosed |