SCHEMBL9477751

SCHEMBL9477751

CCCOc1ccc([C@H]2CC[C@H](C=CF)CC2)cc1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.43
ALDH1A1 P00352 1/20 0.43
MAPT P10636 1/20 0.43
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C19 P33261 1/20 0.41
HRH3 Q9Y5N1 8/20 0.40
CYP2C9 P11712 4/20 0.40
MAOA P21397 2/20 0.40
MAOB P27338 2/20 0.40
KCNH2 Q12809 3/20 0.39
CYP3A4 P08684 3/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
DRD2 P14416 1/20 0.38
CRBN Q96SW2 1/20 0.37
LTA4H P09960 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9477734 1.00 RAB9A (0.43) RAB9AALDH1A1MAPTCYP1A2CYP2D6
SCHEMBL9477745 1.00 RAB9A (0.43) RAB9AALDH1A1MAPTCYP1A2CYP2D6
SCHEMBL9477094 0.96 RAB9A (0.41) RAB9AALDH1A1MAPTCYP1A2CYP2D6
SCHEMBL9477090 0.96 RAB9A (0.41) RAB9AALDH1A1MAPTCYP1A2CYP2D6
SCHEMBL9477570 0.96 RAB9A (0.41) RAB9AALDH1A1MAPTCYP1A2CYP2D6
SCHEMBL9477100 0.96 RAB9A (0.41) RAB9AALDH1A1MAPTCYP1A2CYP2D6
SCHEMBL9477566 0.96 RAB9A (0.41) RAB9AALDH1A1MAPTCYP1A2CYP2D6
SCHEMBL9477560 0.96 RAB9A (0.41) RAB9AALDH1A1MAPTCYP1A2CYP2D6
SCHEMBL9476360 0.94 RAB9A (0.49) RAB9AHRH3CYP2C9MAOAMAOB
SCHEMBL9476366 0.94 RAB9A (0.49) RAB9AHRH3CYP2C9MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0377469-B1 A LIQUID CRYSTALLINE COMPOUND CHISSO CORPORATION (JP) 1993-10-06 EP disclosed
US-5183587-A LIQUID CRYSTALLINE COMPOUND CHISSO CORPORATION (JP) 1993-02-02 US disclosed
EP-0377469-A1 A liquid crystalline compound CHISSO CORPORATION (JP) 1990-07-11 EP disclosed