SCHEMBL9478682

SCHEMBL9478682

CCCCCCCCCCCCCCCCC(OCC(CC)CCCC)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.49
TSHR P16473 2/20 0.49
ATM Q13315 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
PRSS1 P07477 1/20 0.48
PRSS2 P07478 1/20 0.48
PRSS3 P35030 1/20 0.48
LCK P06239 1/20 0.47
PPARD Q03181 1/20 0.47
ZDHHC20 Q5W0Z9 1/20 0.47
ZDHHC2 Q9UIJ5 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.45
GPR84 Q9NQS5 3/20 0.44
FFAR1 O14842 1/20 0.44
CA2 P00918 4/20 0.43
ALDH1A1 P00352 2/20 0.43
MAPT P10636 1/20 0.43
MAPK1 P28482 1/20 0.42
RECQL P46063 1/20 0.41
ACE2 Q9BYF1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24170388 1.00 CYP3A4 (0.49) CYP3A4TSHRATMTDP1PRSS1
SCHEMBL25440562 0.87 CYP3A4 (0.49) CYP3A4TSHRATMTDP1PRSS1
SCHEMBL28023369 0.84 GPR84 (0.44) CYP3A4TSHRATMTDP1PRSS1
SCHEMBL28023354 0.84 GPR84 (0.44) CYP3A4TSHRATMTDP1PRSS1
SCHEMBL9761383 0.80 CYP3A4 (0.39) CYP3A4TSHRATMTDP1PRSS1
SCHEMBL31341787 0.80 GPR84 (0.47) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL5718435 0.80 CYP3A4 (0.54) CYP3A4TSHRATMTDP1PRSS1
SCHEMBL28766385 0.79 GPR84 (0.53) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL8455146 0.79 GPR84 (0.53) LCKPPARDZDHHC20ZDHHC2GPR84
SCHEMBL30775240 0.79 GPR84 (0.53) LCKPPARDZDHHC20ZDHHC2GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0291334-B1 TRANSPARENT ANTIPERSPIRANT STICK COMPOSITIONS UNILEVER PLC (GB) 1993-09-08 EP claimed
EP-0254447-B1 PROCESS FOR PRODUCING POLYMER-THICKENED OIL MACROCAPSULES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-03-17 EP claimed
US-4948578-A MIXTURE OF ALUMINUM SALT, NONIONIC SURFACTANT, OIL, AND WATER LEVER BROTHERS COMPANY (US) 1990-08-14 US claimed
EP-0291334-A2 Transparent antiperspirant stick compositions UNILEVER PLC (GB) 1988-11-17 EP claimed
EP-0061701-B1 A SOLID ENTRAPPED EMOLLIENT-MOISTURIZER COMPOSITION AND THE USE THEREOF Wickhen Products, Inc. (US) 1986-07-16 EP claimed
CN-104603120-A A process for the preparation of karanja oil-based epoxy and acyloxy compounds as lubricant basestocks COUNCIL SCIENT IND RES 2015-05-06 CN disclosed
EP-0291334-B1 TRANSPARENT ANTIPERSPIRANT STICK COMPOSITIONS UNILEVER PLC (GB) 1993-09-08 EP disclosed
US-5208038-A Polymers with particles entrapped DOW CORNING CORPORATION (US) 1993-05-04 US disclosed
US-5126309-A Macroporous crosslinked hydrophobic copolymer particles having voids which can carry and release active chemicals to react with contaminants DOW CORNING CORPORATION (US) 1992-06-30 US disclosed
US-5102662-A Unexpanded resin with uniformly dispersed particles of crosslinked macroporous hydrophobic polymer containing trapped insect repellent DOW CORNING CORPORATION (US) 1992-04-07 US disclosed
US-5100477-A Macroporous Crosslinked Hydrophobic Copolymer DOW CORNING CORPORATION (US) 1992-03-31 US disclosed
US-5037485-A Removing a stain with hydrophilic polymer; adsorption; absorption; textiles; eyeglass lenses; dentures DOW CORNING CORPORATION (US) 1991-08-06 US disclosed
EP-0407095-A1 Fragrance release device containing a highly adsorptive copolymer DOW CORNING CORPORATION (US) 1991-01-09 EP disclosed
EP-0398538-A1 Method of making hydrophilic-lipophilic copolymeric powders DOW CORNING CORPORATION (US) 1990-11-22 EP disclosed
EP-0398537-A1 Decontamination of toxic chemical agents DOW CORNING CORPORATION (US) 1990-11-22 EP disclosed
EP-0393510-A1 Method of making highly adsorptive copolymers DOW CORNING CORPORATION (US) 1990-10-24 EP disclosed
US-4961532-A MULTICHAMBER CONTAINER, HERMETIC SEALING, AIR PERMEABLE, CARRIERS, PARTICLES, AGGLOMERATION DOW CORNING CORPORATION (US) 1990-10-09 US disclosed
US-4948818-A PRECIPITATION COPOLYMERIZING AT LEAST ONE MONO-AND AT LEAST ONE POLYUNSATURATED MONOMER DOW CORNING CORPORATION (US) 1990-08-14 US disclosed
US-4948578-A MIXTURE OF ALUMINUM SALT, NONIONIC SURFACTANT, OIL, AND WATER LEVER BROTHERS COMPANY (US) 1990-08-14 US disclosed
EP-0291334-A2 Transparent antiperspirant stick compositions UNILEVER PLC (GB) 1988-11-17 EP disclosed