Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 7/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9480354 | 0.90 | AGTR1 (0.47) | PTGER1AGTR1AGTR2 | |
| SCHEMBL9492039 | 0.88 | PTGER1 (0.42) | PTGER1AGTR1AGTR2 | |
| SCHEMBL9492035 | 0.83 | AGTR1 (0.43) | PTGER1AGTR1AGTR2 | |
| SCHEMBL9480600 | 0.82 | AGTR1 (0.34) | PTGER1AGTR1 | |
| SCHEMBL7049483 | 0.82 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL9481020 | 0.80 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL9492042 | 0.80 | PTGER1 (0.40) | PTGER1AGTR1AGTR2 | |
| SCHEMBL9309709 | 0.77 | AGTR1 (0.65) | AGTR1AGTR2 | |
| SCHEMBL9427972 | 0.76 | PPARG (0.57) | AGTR1AGTR2 | |
| SCHEMBL9481790 | 0.75 | AGTR1 (0.39) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559724-A1 | BENZOFURAN AND BENZTHIOPHENE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1993-09-15 | — | — | EP | disclosed |
| WO-1992009600-A1 | BENZOFURAN AND BENZTHIOPHENE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1992-06-11 | — | — | WO | disclosed |