Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | LSS | P48449 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9480426 | 1.00 | PTGS2 (0.57) | PTGS2HTTPOLBAPEX1TDP1 | |
| SCHEMBL8897411 | 0.96 | HTT (0.57) | PTGS2HTTPOLBAPEX1TDP1 | |
| SCHEMBL10333121 | 0.96 | HTT (0.57) | PTGS2HTTPOLBAPEX1TDP1 | |
| SCHEMBL8897407 | 0.96 | HTT (0.57) | PTGS2HTTPOLBAPEX1TDP1 | |
| SCHEMBL9133114 | 0.94 | PTGS2 (0.56) | PTGS2HTTPOLBAPEX1TDP1 | |
| SCHEMBL10479349 | 0.91 | PTGS2 (0.49) | PTGS2HTTPOLBAPEX1TDP1 | |
| SCHEMBL10333148 | 0.90 | MAPT (0.49) | PTGS2HTTPOLBAPEX1TDP1 | |
| SCHEMBL10332681 | 0.88 | PTGS2 (0.47) | PTGS2HTTPOLBAPEX1TDP1 | |
| SCHEMBL9332678 | 0.85 | POLB (0.61) | HTTPOLBAPEX1TDP1MAPT | |
| SCHEMBL10397395 | 0.84 | EPHX1 (0.47) | PTGS2HTTPOLBAPEX1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5224196-A | Waveguide device and method for phase matched second harmonic generation | HOECHST CELANESE CORP. | 1993-06-29 | — | — | US | disclosed |