SCHEMBL9480487

SCHEMBL9480487

CCCCC(Cn1cncn1)c1ccc(C)cc1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 3/20 0.42
ALDH1A1 P00352 2/20 0.42
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CYP19A1 P11511 2/20 0.40
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
HSP90AA1 P07900 1/20 0.37
HRH3 Q9Y5N1 1/20 0.37
CYP17A1 P05093 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10972636 0.87 NPSR1 (0.48) NPSR1ALDH1A1MEN1KMT2ACYP19A1
Ammonia Solution, Strong SCHEMBL9422751 0.86 CYP19A1 (0.42) ALDH1A1MEN1KMT2ACYP19A1CYP3A4
SCHEMBL9480234 0.82 TSHR (0.46) ALDH1A1MEN1KMT2ACYP19A1CYP1A2
SCHEMBL9482419 0.82 KMT2A (0.42) NPSR1ALDH1A1MEN1KMT2ACYP19A1
SCHEMBL9480588 0.82 OPRM1 (0.36) NPSR1ALDH1A1MEN1KMT2ACYP1A2
Hydrochloric Acid SCHEMBL9481865 0.81 KMT2A (0.41) NPSR1ALDH1A1MEN1KMT2ACYP19A1
SCHEMBL10832795 0.78 CYP19A1 (0.53) NPSR1ALDH1A1MEN1KMT2ACYP19A1
SCHEMBL10833575 0.78 CYP3A4 (0.46) NPSR1ALDH1A1MEN1KMT2ACYP19A1
Hydrochloric Acid SCHEMBL10833300 0.77 CYP3A4 (0.46) NPSR1ALDH1A1MEN1KMT2ACYP19A1
Hydrochloric Acid SCHEMBL10832134 0.77 CYP19A1 (0.52) NPSR1ALDH1A1MEN1KMT2ACYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5192783-A Fungicides for plants ROHM AND HAAS COMPANY (US) 1993-03-09 US disclosed