Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28695553 | 0.89 | KDM4E (0.50) | CFTRCA1CA2CA9KDM4E | |
| SCHEMBL14666358 | 0.89 | CFTR (0.53) | CFTRCA12CA1CA2CA7 | |
| SCHEMBL4980293 | 0.88 | KDM4E (0.53) | CFTRCA1CA2CA9KDM4E | |
| SCHEMBL8383099 | 0.86 | PTPN11 (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9618201 | 0.84 | CA12 (0.50) | CFTRCA12CA1CA2CA7 | |
| SCHEMBL28694398 | 0.81 | CA12 (0.48) | CFTRCA12CA1CA2CA7 | |
| SCHEMBL15903170 | 0.79 | CFTR (0.53) | CFTRCA12CA1CA2CA7 | |
| SCHEMBL25455691 | 0.79 | CFTR (0.46) | CFTRCA12CA1CA2CA7 | |
| SCHEMBL23364330 | 0.79 | KDM4E (0.61) | KDM4EALDH1A1HPGDTSHRGAA | |
| SCHEMBL28922445 | 0.78 | CFTR (0.66) | CFTRCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216118-A | Preparation of aromatic polyimides from CO, primary diamine and bis (halo aromatic carboxylic acid ester) | EASTMAN KODAK COMPANY (US) | 1993-06-01 | — | — | US | disclosed |