Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.48 |
| ▸ | APP | P05067 | 2/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL9482134 | 0.95 | ANPEP (0.45) | ANPEPMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9480735 | 0.88 | HRH3 (0.46) | ANPEPMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9481024 | 0.87 | HRH3 (0.46) | ANPEPMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9480667 | 0.86 | HRH3 (0.57) | MEN1KMT2AKDM4EALDH1A1HRH3 | |
| SCHEMBL9481237 | 0.84 | KDM4E (0.49) | MEN1KMT2AKDM4EALDH1A1HRH3 | |
| SCHEMBL9482297 | 0.79 | HRH3 (0.51) | ANPEPMEN1KMT2AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9481001 | 0.78 | HRH3 (0.50) | ANPEPMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9481249 | 0.78 | BACE1 (0.60) | MEN1KMT2AKDM4EALDH1A1HRH3 | |
| SCHEMBL9483689 | 0.77 | HRH3 (0.54) | MEN1KMT2AKDM4EALDH1A1HRH3 | |
| SCHEMBL9481058 | 0.76 | HRH3 (0.51) | MEN1KMT2AKDM4EALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216165-A | N-substituted aminoquinolines as analgesic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-06-01 | — | — | US | claimed |
| US-5216165-A | N-substituted aminoquinolines as analgesic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |