Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9481024 | 0.98 | HRH3 (0.46) | HRH3ANPEPAPPMEN1KMT2A | |
| SCHEMBL9482297 | 0.92 | HRH3 (0.51) | HRH3ANPEPAPPMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9481001 | 0.91 | HRH3 (0.50) | HRH3ANPEPAPPMEN1KMT2A | |
| SCHEMBL9480625 | 0.88 | ANPEP (0.49) | HRH3ANPEPAPPMEN1KMT2A | |
| SCHEMBL9480811 | 0.86 | APP (0.46) | HRH3APPMEN1KMT2AKDM4E | |
| SCHEMBL9480688 | 0.86 | UBE2M (0.53) | HRH3OPRM1UBE2MDCUN1D1 | |
| SCHEMBL9481187 | 0.85 | OPRM1 (0.52) | HRH3APPMEN1KMT2AKDM4E | |
| SCHEMBL9481058 | 0.85 | HRH3 (0.51) | HRH3APPMEN1KMT2AKDM4E | |
| Trifluoroacetic Acid SCHEMBL9482134 | 0.84 | ANPEP (0.45) | HRH3ANPEPAPPMEN1KMT2A | |
| SCHEMBL9481084 | 0.83 | HRH3 (0.49) | HRH3APPMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216165-A | N-substituted aminoquinolines as analgesic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-06-01 | — | — | US | claimed |
| US-5216165-A | N-substituted aminoquinolines as analgesic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |