Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28852837 | 1.00 | ALDH1A1 (0.52) | ALDH1A1LMNATRPA1ALOX5MAPK1 | |
| SCHEMBL264894 | 0.87 | MAOB (0.55) | ALDH1A1LMNATRPA1ALOX5MAPK1 | |
| SCHEMBL264895 | 0.87 | MAOB (0.55) | ALDH1A1LMNATRPA1ALOX5MAPK1 | |
| SCHEMBL31635870 | 0.80 | EGFR (0.55) | ALDH1A1EGFRCYP2A6MAPTTDP1 | |
| SCHEMBL15946401 | 0.78 | MAOB (0.46) | ALDH1A1LMNATRPA1ALOX5MAPK1 | |
| SCHEMBL11498707 | 0.78 | ALDH1A1 (0.46) | ALDH1A1LMNATRPA1ALOX5MAPK1 | |
| SCHEMBL1507418 | 0.77 | MAOB (0.50) | ALDH1A1LMNATRPA1ALOX5MAPK1 | |
| SCHEMBL12719046 | 0.77 | MAOB (0.50) | ALDH1A1LMNATRPA1ALOX5MAPK1 | |
| SCHEMBL991992 | 0.77 | NPC1 (0.52) | ALDH1A1LMNATRPA1ALOX5MAPK1 | |
| SCHEMBL17995260 | 0.77 | MAOB (0.50) | ALDH1A1LMNATRPA1ALOX5MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200891-B | Preparation method of cis-N-styryl amide derivative | 华侨大学 | 2022-09-30 | — | — | CN | claimed |
| CN-113200891-A | Preparation method of cis-N-styryl amide derivative | 华侨大学 | 2021-08-03 | — | — | CN | claimed |
| CN-113200891-B | Preparation method of cis-N-styryl amide derivative | 华侨大学 | 2022-09-30 | — | — | CN | disclosed |
| CN-113200891-A | Preparation method of cis-N-styryl amide derivative | 华侨大学 | 2021-08-03 | — | — | CN | disclosed |
| CN-1098260-C | 2,4-diaminopyrimidine derivatives | BASLIR PHARMACEUTICALS AG (CH) | 2003-01-08 | — | — | CN | disclosed |
| CN-1218465-A | 2,4-diaminopyrimidine derivatives | HOFFMANN LA ROCHE (CH) | 1999-06-02 | — | — | CN | disclosed |
| US-5208341-A | Pressure sensitive copying; thermoreactive or electrochromic recording materials | BAYER AKTIENGESELLSCHAFT (DE) | 1993-05-04 | — | — | US | disclosed |
| EP-0480276-A2 | Carbonylaminostyrene derivatives as recording material | BAYER AG (DE) | 1992-04-15 | — | — | EP | disclosed |
| EP-0480276-A2 | Carbonylaminostyrene derivatives as recording material | BAYER AG (DE) | 1992-04-15 | — | — | EP | disclosed |