Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.53 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | PTGFR | P43088 | 5/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | SLCO2A1 | Q92959 | 1/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9480759 | 1.00 | ALDH1A1 (0.53) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL10631786 | 1.00 | ALDH1A1 (0.53) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL10631782 | 1.00 | ALDH1A1 (0.53) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL10626353 | 0.93 | ALDH1A1 (0.45) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL10626358 | 0.93 | ALDH1A1 (0.45) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL11159968 | 0.92 | ALDH1A1 (0.53) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL11071519 | 0.92 | ALDH1A1 (0.53) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL11071515 | 0.92 | ALDH1A1 (0.53) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL11161330 | 0.92 | ALDH1A1 (0.53) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL11431537 | 0.92 | ALDH1A1 (0.53) | ALDH1A1KDM4EHKDC1TDP1SAE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204371-A | Pharmaceutically active 9-chloroprostaglandins | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-04-20 | — | — | US | disclosed |
| US-5079259-A | PHARMACEUTICALLY ACTIVE 9-CHLOROPROSTAGLANDINS | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-01-07 | — | — | US | disclosed |
| US-4560786-A | Δ8,9 -Prostaglandin derivatives, their preparation and use as medicinal agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-12-24 | — | — | US | disclosed |
| US-4454339-A | 9-Fluoroprostaglandin derivatives, and use as medicinal agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-06-12 | — | — | US | disclosed |
| US-4444788-A | Pharmaceutically active 9-chloroprostaglandins | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-04-24 | — | — | US | disclosed |