Styrene

Styrene

SCHEMBL9480922

C=CCCC.C=Cc1ccccc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.61
ALDH1A1 P00352 3/20 0.61
TDP1 Q9NUW8 2/20 0.39
TP53 P04637 1/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
HDAC8 Q9BY41 2/20 0.37
RELA Q04206 1/20 0.34
TAS1R3 Q7RTX0 1/20 0.34
TAS1R1 Q7RTX1 1/20 0.34
LMNA P02545 1/20 0.33
ACHE P22303 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
IDH1 O75874 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL11199361 1.00 TSHR (0.61) TSHRALDH1A1TDP1TP53MEN1
Styrene SCHEMBL17224969 0.88 TSHR (0.56) TSHRALDH1A1TDP1TP53MEN1
Styrene SCHEMBL28474608 0.88 TSHR (0.56) TSHRALDH1A1TDP1TP53MEN1
Styrene SCHEMBL93585 0.86 ALDH1A1 (0.74) TSHRALDH1A1TDP1TP53MEN1
Styrene SCHEMBL290213 0.86 ALDH1A1 (0.74) TSHRALDH1A1TDP1TP53MEN1
Styrene SCHEMBL364050 0.86 ALDH1A1 (0.74) TSHRALDH1A1TDP1TP53MEN1
Styrene SCHEMBL20153440 0.86 ALDH1A1 (0.74) TSHRALDH1A1TDP1TP53MEN1
Styrene SCHEMBL15284814 0.86 TSHR (0.56) TSHRALDH1A1TDP1TP53MEN1
Styrene SCHEMBL27467154 0.86 TSHR (0.54) TSHRALDH1A1TDP1TP53MEN1
Styrene SCHEMBL22799283 0.84 TSHR (0.59) TSHRALDH1A1TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1633628-A Resist compositions WAKO PURE CHEM IND LTD (JP) 2005-06-29 CN disclosed
US-5213740-A Processes for the preparation of toner compositions XEROX CORPORATION (US) 1993-05-25 US disclosed